Linear 1 3-diarylpropanoids
![eMolecules 247129-88-0 | Diphenyl-vinyl-sulfonium triflate | J&W PharmLab LLC | MFCD22123284 | 362.380 | C15H13F3O3S2 | 95.000 | [O-]S(=O)(=O)C(F)(F)F.C=C[S+](c1ccccc1)c1ccccc1 | 100mg | 600881580](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 247129-88-0 | Diphenyl-vinyl-sulfonium triflate | J&W PharmLab LLC | MFCD22123284 | 362.380 | C15H13F3O3S2 | 95.000 | [O-]S(=O)(=O)C(F)(F)F.C=C[S+](c1ccccc1)c1ccccc1 | 100mg | 600881580
Diphenyl-vinyl-sulfonium triflate | J&W PharmLab LLC | 247129-88-0 | MFCD22123284 | 362.380 | C15H13F3O3S2 | 95.000 | [O-]S(=O)(=O)C(F)(F)F.C=C[S+](c1ccccc1)c1ccccc1 | 100mg | 600881580
Medchemexpress LLC Isodecyl diphenyl phosphate | 29761-21-5 | MFCD00072254 | 390.45 g/mol | C22H31O4P | 25mg
Isodecyl diphenyl phosphate (IDPP) is a flame retardant IDPP has an ability to induce DNA damage and exertes S phase cell ratio-reducing effects in A549 cells[1]
Aobchem 1-Propanone 1-(4-bromo-2-methylphenyl)-2-methyl- | 95% | CAS 857732-00-4 | C11H13BrO | 1g
1-Propanone 1-(4-bromo-2-methylphenyl)-2-methyl- | 95% | CAS 857732-00-4 | C11H13BrO | 1g
Aobchem 1-Propanone 1-(4-bromo-2-methylphenyl)-2-methyl- | 95% | CAS 857732-00-4 | C11H13BrO | 500mg
1-Propanone 1-(4-bromo-2-methylphenyl)-2-methyl- | 95% | CAS 857732-00-4 | C11H13BrO | 500mg
Medchemexpress LLC 4'-Methoxychalcone | 959-23-9 | 99.8% | 5 G
4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. It also modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity. This product is intended for research use only.
- Regulates adipocyte differentiation via PPARγ activation
- Modulates adipokine expression and secretion involved in insulin sensitivity
- Increases mRNA expression of adipogenic genes during differentiation
- Reduces upregulated mRNA expression of IL-6, PAI-1, and MCP-1
- Causes an increase in PPARγ expression during differentiation
- Exhibits antiproliferative activity and cytotoxicity against various human cell lines
- Targets PPARγ
- Derived from Piperaceae Piper nigrum Linn.
- Classified as flavonoids, chalcones
Medchemexpress LLC PI3K/AKT-IN-1 | 3033069-84-7 | 99.6% | C23H23N5O4S | 25 MG
PI3K/AKT-IN-1 is an effective dual inhibitor of PI3K and AKT, exhibiting anticancer activity by inhibiting the PI3K/AKT axis and inducing caspase 3-dependent apoptosis. This compound has high cytotoxic activity against leukemia K562 and breast cancer MCF-7 cell lines, and is intended for research use only.
- Demonstrates high cytotoxic activity, particularly against leukemia cell line K562 (IC50=2.62 μM) and breast cancer cell line MCF-7 (IC50=3.22 μM)
- Promotes S-phase cell cycle arrest and induces apoptosis in K562 cells
- Significantly reduces the expression of PI3K, p-PI3K, AKT, p-AKT, Cyclin D1, and NF-κB
- Found to be non-toxic and well-tolerated in animal studies, with an LD50 greater than 2000 mg/kg
- Soluble in DMSO at 50 mg/mL
- Solid, off-white to light yellow appearance
Medchemexpress LLC Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) | 4197-97-1 | 5 MG
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound isolated from Helichrysum Trilineatum. It facilitates AMP-activated protein kinase (AMPK) activation, which improves glucose tolerance, increases muscle fatty acid oxidation (FAO), and reduces fat accumulation in the liver and skeletal muscles of high-fat diet-induced (HFD) diabetic mice. These properties make Pinocembrin chalcone a promising compound for research related to gastric ulcers and diabetes.
- Antibacterial activity: Inhibits the growth of S. aureus in vitro.
- Metabolic regulation: Significantly increases the fatty acid oxidation rate and enhances the phosphorylation of AMPKα in C2C12 myotubes.
- Anti-diabetic effects: Improves glucose tolerance and reduces fat accumulation in the liver and muscles in HFD-induced diabetic mice.
Aobchem 1-Propanone 1-(4-fluoro-2-methylphenyl)- | 95% | CAS 575-68-8 | C10H11FO | 500mg
1-Propanone 1-(4-fluoro-2-methylphenyl)- | 95% | CAS 575-68-8 | C10H11FO | 500mg
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | MFCD00006844 | 99.83% | 272.26 | 1 ML
(±)-Naringenin is an orally available anti-inflammatory agent that regulates acute and chronic inflammation, and exhibits antioxidant, neuroprotective, liver-protective, and anti-cancer effects. It promotes vasodilation and protects against experimental colitis by inhibiting Toll-like receptor 4/NF-κB signaling, useful in studies of sepsis, fulminant hepatitis, fibrosis, and cancer. It appears as an off-white to light yellow solid.
- Regulates acute and chronic inflammation.
- Antioxidant, neuroprotective, liver-protective, and anti-cancer effects.
- Promotes vasodilation.
- Protects against experimental colitis.
- Useful in sepsis, hepatitis, fibrosis, and cancer research.
- Orally available.
Aobchem Trans-4 -Hydroxychalcone | 95% | CAS 38239-52-0 | C15H12O2 | 5g
Trans-4 -Hydroxychalcone | 95% | CAS 38239-52-0 | C15H12O2 | 5g